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Prevention, Diagnosis and Treatment of Opportunistic Infections in HIV-infected Adults and Adolescents 2016

Published by the Philippine Society for Microbiology and Infectious Diseases (PSMID), Inc., ISBN: 978-971-94818-3-6

This guideline is intended for the use of a broad range of healthcare professionals including medical specialists, clinical practitioners, nurses, administrators and policy makers.

Background: Human Immunodeficiency Virus (HIV) is the causative agent of Acquired Immune Deficiency Syndrome (AIDS). HIV infection affects 33.3 million people worldwide, with 2.6 million new cases annually. Over the last decade, major advances in the understanding and treatment of HIV have led to a dramatic decrease in AIDS-related deaths to the point that this once inevitably fatal disease has been transformed into a chronic illness. From 2001 to 2009, 33 countries have decreased HIV incidence by over 25%, while 23 others have stabilized their case numbers. The Philippines is one of only seven countries, and the only one in Southeast Asia, to have seen an increase of more than 25% HIV prevalence in this time period (UNAIDS, 2011). While doubling time for new cases in the Philippines took 10 years from 1996 to 2006, acceleration of the doubling time to just 2 years between 2007 and 2009, and to 1 year from 2009 to 2010 is alarming. New infections are currently being diagnosed at a rate of six new cases per day (NEC, 2012). The DOH declared an HIV epidemic in July 2010, and case numbers continue to increase. While government and private efforts to address the epidemic through ramped up prevention and education programs and the provision of specialized clinical care and free antiretroviral (ARV) treatment have been met with some success, the rapid increase in case numbers threatens to overwhelm the limited resources and expertise available. The rapid increase of persons presenting in full-blown AIDS with opportunistic infections (OIs) that most Filipino physicians are unfamiliar with has led to a delay in recognition as well as inappropriate or inadequate treatment (Farr and Wilson, 2010).

Philippine Clinical Practice Guidelines for the Prevention, Diagnosis, and Treatment of Opportunistic Infections in Human Immunodeficiency Virus-Infected Adults and Adolescents in the Philippines 2016

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